YBX1 anticorps (CF®594)
Aperçu rapide pour YBX1 anticorps (CF®594) (ABIN7662075)
Antigène
Voir toutes YBX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- YBX1 / Y-box Binding Protein 1 / YB-1 (Tumor Biomarker)(YBX1/2430), CF594 conjugate
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Attributs du produit
- The specificity of this monoclonal antibody to its intended target was validated by HuProt™, Array, containing more than 19,000 full-length human proteins. Y-box binding protein-1 (YBX1) is the prototypic member of the cold shock protein family that fulfills numerous cellular functions. In the nucleus, YBX1 protein orchestrates transcription of proliferation-related genes, whereas in the cytoplasm it associates with mRNA and directs translation. In human tumor entities, such as breast, lung and prostate cancer, cellular YBX1 expression indicates poor clinical outcome, suggesting that YBX1 is an attractive marker to predict patients' prognosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogène
- Recombinant human full-length YBX1 protein
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Isotype
- IgG2b, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Positive Control: MCF-7, HEK293 or PC12 cells. Prostate, Breast or Lung Carcinoma.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.1 % BSA, 0.05 % azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Protect from light
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Stock
- 4 °C
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Stockage commentaire
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Stable at room temperature or 37°C for 7 days.
Protect from light
Store at 2 to 8°C. Protect fluorescent conjugates from light
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Date de péremption
- 24 months
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- YBX1 (Y Box Binding Protein 1 (YBX1))
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Autre désignation
- Y-box Binding Protein 1
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Sujet
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Synonyms: BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1
Gene Symbol: YBX1
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Poids moléculaire
- 36 kDa
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ID gène
- 4904
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UniProt
- P67809
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Pathways
- Regulation of Muscle Cell Differentiation
Antigène
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